Genetic basis of rotator cuff injury: a systematic review.

ABSTRACT:

Background

Rotator cuff disease is a widespread musculoskeletal pathology and a major cause of shoulder pain. Studies on familial predisposition suggest that genetic plays a role in the pathogenesis of rotator cuff disease. Several genes are responsible for rotator cuff disease. The aim of this study was to perform a systematic review on genetic association between rotator cuff disease and genes variations.

Methods

A systematic review of the literature was performed, in accordance with the PRISMA guidelines. PubMed, Medline, CINAHL, Cochrane, Embase and Google Scholar databases were searched comprehensively using the keywords: "Rotator cuff", "Gene", "Genetic", "Predisposition", "Single-nucleotide polymorphism" and "Genome-wide association".

Results

8 studies investig

SUBMITTER: Longo UG 

PROVIDER: S-EPMC6720871 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature