Dynamics of transcriptome changes during subcutaneous preadipocyte differentiation in ducks.

ABSTRACT:

Background

Pekin duck is an important animal model for its ability for fat synthesis and deposition. However, transcriptional dynamic regulation of adipose differentiation driven by complex signal cascades remains largely unexplored in this model. This study aimed to explore adipogenic transcriptional dynamics before (proliferation) and after (differentiation) initial preadipocyte differentiation in ducks.

Results

Exogenous oleic acid alone successfully induced duck subcutaneous preadipocyte differentiation. We explored 36 mRNA-seq libraries in order to study transcriptome dynamics during proliferation and differentiation processes at 6 time points. Using robust statistical analysis, we identified 845, 652, 359, 2401 and 1933 genes differentially expressed between -48 h and

SUBMITTER: Wang Z 

PROVIDER: S-EPMC6720933 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature