Treatment resistant depression in women with peripartum depression.

ABSTRACT:

Background

Peripartum depression is a leading cause of disease burden for women and yet there is little evidence as to how often peripartum depression does not respond to treatment and becomes treatment resistant depression. We sought to determine the incidence of treatment resistant depression (TRD) in women with peripartum depression.

Methods

Population based retrospective cohort study using a large US claims database. Peripartum depression was defined as having a depression diagnosis during pregnancy or up to 6 months after the end of pregnancy. We included women with prevalent or incident depression. The outcome was the development of TRD within 1 year after the diagnosis of peripartum depression. TRD was defined as having 3 distinct antidepressants or 1 antidepressant a

SUBMITTER: Cepeda MS 

PROVIDER: S-EPMC6721276 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature