Clinical onset of atopic eczema: Results from 2 nationally representative British birth cohorts followed through midlife.

ABSTRACT:

Background

Atopic eczema onset is described primarily in early childhood, and the frequency and characteristics of adult-onset disease remain controversial.

Objective

We sought to determine the proportion of subjects who report atopic eczema symptoms between birth and midadulthood and to examine demographic, immunologic, and genetic factors associated with period of symptom onset.

Methods

We conducted a longitudinal study using data from 2 nationally representative community-based birth cohorts from the United Kingdom: the British Cohort Studies 1958 and 1970. Subjects were followed from birth through age 42 to 50 years. The primary outcome was the age period of self-reported atopic eczema symptom onset based on repeated measures of self-reported atopic eczema at each

SUBMITTER: Abuabara K 

PROVIDER: S-EPMC6721832 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature