Voltage during atrial fibrillation is superior to voltage during sinus rhythm in localizing areas of delayed enhancement on magnetic resonance imaging: An assessment of the posterior left atrium in patients with persistent atrial fibrillation.

ABSTRACT:

Background

Bipolar electrogram voltage during sinus rhythm (V_SR) has been used as a surrogate for atrial fibrosis in guiding catheter ablation of persistent atrial fibrillation (AF), but the fixed rate and wavefront characteristics present during sinus rhythm may not accurately reflect underlying functional vulnerabilities responsible for AF maintenance.

Objective

The purpose of this study was determine whether, given adequate temporal sampling, the spatial distribution of mean AF voltage (V_mAF) better correlates with delayed-enhancement magnetic resonance imaging (MRI-DE)-detected atrial fibrosis than V_SR.

Methods

AF was mapped (8 seconds) during index ablation for persistent AF (20 patients) using a 20-pole catheter (660 ± 28 points/

SUBMITTER: Qureshi NA 

PROVIDER: S-EPMC6722483 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature