Prebiotics: Mechanisms and Preventive Effects in Allergy.

ABSTRACT: Allergic diseases now affect over 30% of individuals in many communities, particularly young children, underscoring the need for effective prevention strategies in early life. These allergic conditions have been linked to environmental and lifestyle changes driving the dysfunction of three interdependent biological systems: microbiota, epithelial barrier and immune system. While this is multifactorial, dietary changes are of particular interest in the altered establishment and maturation of the microbiome, including the associated profile of metabolites that modulate immune development and barrier function. Prebiotics are non-digestible food ingredients that beneficially influence the health of the host by 1) acting as a fermentable substrate for some specific commensal host bacteria leadi

SUBMITTER: Brosseau C 

PROVIDER: S-EPMC6722770 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature