Sex differences in tobacco withdrawal and responses to smoking reduced-nicotine cigarettes in young smokers.

ABSTRACT:

Rationale

Policies that establish a standard for reduced nicotine content in cigarettes can decrease the prevalence of smoking in the USA. Cigarettes with nicotine yields as low as 0.05 mg produce substantial occupancy of nicotinic acetylcholine receptors (26%), but women and men respond differently to these cigarettes.

Objective

This study aimed to measure responses to smoking cigarettes that varied widely in nicotine yields, investigating whether sex differences in the effects on craving, withdrawal, and affect would be observed at even lower nicotine yields than previously studied, and in young smokers.

Methods

Overnight abstinent young smokers (23 men, 23 women, mean age 22.18) provided self-reports of craving, withdrawal, and affect before and after smoking cigar

SUBMITTER: Faulkner P 

PROVIDER: S-EPMC6726112 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature