Quantification of movement in normal and parkinsonian macaques using video analysis.

ABSTRACT:

Background

Quantification of spontaneous animal movement can be achieved using analysis of video recordings of the animals. Previous reports of video-based methods are based on outdated computer platforms or require the use of specialized equipment.

New method

We developed a video analysis algorithm to quantify movement based on the commonly used MATLAB programming language. The algorithm is based on pixel differences between frames of video footage acquired with a standard video camera.

Results

The new algorithm was validated, analyzing the amount of movements made by monkeys undergoing treatment with the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to induce parkinsonism. We compared the movement quantification generated by the new sys

SUBMITTER: Caiola M 

PROVIDER: S-EPMC6726117 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature