CiiiDER: A tool for predicting and analysing transcription factor binding sites.

ABSTRACT: The availability of large amounts of high-throughput genomic, transcriptomic and epigenomic data has provided opportunity to understand regulation of the cellular transcriptome with an unprecedented level of detail. As a result, research has advanced from identifying gene expression patterns associated with particular conditions to elucidating signalling pathways that regulate expression. There are over 1,000 transcription factors (TFs) in vertebrates that play a role in this regulation. Determining which of these are likely to be controlling a set of genes can be assisted by computational prediction, utilising experimentally verified binding site motifs. Here we present CiiiDER, an integrated computational toolkit for transcription factor binding analysis, written in the Java programming

SUBMITTER: Gearing LJ 

PROVIDER: S-EPMC6726224 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature