The complete genome sequence of Bifidobacterium animalis subsp. lactis 01 and its integral components of antioxidant defense system.

ABSTRACT: The strain Bifidobacterium animalis 01, isolated from centenarians, showed promising antioxidant potential in our previous studies. In this study, the genome information on strain 01 and the important antioxidant components are presented. The complete genome comprises a single circular chromosome (1,931,632 bp; 60.49% G + C content) with 1569 coding DNA sequences, 52 tRNA, and 9 rRNA operons. Based on phylogenomic analyses, strain 01 was designated as B. animalis subsp. lactis 01. The genomic analysis reveals that at least eight protein-coding genes are antioxidant-related genes. The conditions for simulating the oxidative stress have been determined. The results of quantitative reverse transcription PCR further demonstrated that the genes encoding the thioredoxin syst

SUBMITTER: Zhang J 

PROVIDER: S-EPMC6726729 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature