Disseminated Mycobacterium ulcerans Infection in Wild Grasscutters (Thryonomys swinderianus), Cote d'Ivoire.

ABSTRACT: Buruli ulcer is an infectious disease provoking chronic, disabling skin ulcers in mammals and humans. Buruli ulcer is caused by Mycobacterium ulcerans, an environmental mycobacterium synthesizing a toxin called mycolactone responsible for the pathogenicity. The reservoirs and the modes of transmission of M. ulcerans remain elusive, limiting the prophylaxis capabilities in rural areas in endemic countries. In Australia, several studies have demonstrated the probable role of possums as reservoirs. In Côte d'Ivoire, some studies have speculated on the potential role of grasscutters in the transmission cycle of M. ulcerans. In this study, we detected M. ulcerans-specific sequences in rectal contents and spleens collected in wild grasscutters hunted in Buruli ulcer-e

SUBMITTER: Hammoudi N 

PROVIDER: S-EPMC6726967 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature