Lifestyle of women before pregnancy and the risk of offspring obesity during childhood through early adulthood.

ABSTRACT:

Background

In women, adhering to an overall healthy lifestyle is associated with a dramatically reduced risk of cardio-metabolic disorders. Whether such a healthy lifestyle exerts an intergenerational effects on child health deserves examination.

Methods

We included 5701 children (9-14 years old at baseline) of the Growing Up Today Study 2, and their mothers, who are participants in the Nurses' Health Study II. Pre-pregnancy healthy lifestyle was defined as a normal body mass index, no smoking, physical activity ≥150 min/week, and diet in the top 40% of the Alternative Healthy Eating Index-2010. Obesity during childhood and adolescence was defined using the International Obesity Task Force age- and sex-specific cutoffs. Multivariable log-binominal regression models with gene

SUBMITTER: Dhana K 

PROVIDER: S-EPMC6727198 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature