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Renal denervation in patients with symptomatic chronic heart failure despite resynchronization therapy - a pilot study.


ABSTRACT:

Introduction

Renal denervation (RD) has been shown to decrease sympathetic function in patients with hypertension. Its efficacy in symptomatic chronic heart failure (CHF) patients not responding to cardiac resynchronization therapy (CRT) has not been evaluated.

Aim

To assess whether a less invasive treatment method - renal denervation - is safe in symptomatic heart failure patients despite optimal medical treatment and resynchronization therapy and whether it is associated with an improvement in clinical status, exercise capacity and hemodynamic parameters.

Material and methods

The study was an open-label, randomized, controlled clinical trial. Patients were divided into an intervention (RD) and a control group. Clinical data collection, blood pressure (BP) measuremen

SUBMITTER: Drozdz T 

PROVIDER: S-EPMC6727225 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature