No radiographic wrist damage after treatment to target in recent-onset juvenile idiopathic arthritis.

ABSTRACT: BACKGROUND:To evaluate radiographic progression of patients with new-onset juvenile idiopathic arthritis (JIA) in response to an early, tightly-controlled, treatment-to-target. METHODS:Patients with JIA participating in the BeSt-for-Kids-study, randomized to 3 treatment strategy arms, were eligible if at least 1 conventional wrist-radiograph was available. Bone damage as reflected by carpal length was assessed using the Poznanski-score. The BoneXpert-method was used to determine the Bone Age (BA, > 5 years) and bone mineral density (BMD) of the wrist. These scores were evaluated over time and compared between the treatment arms and mean JADAS10-score using linear mixed models corrected for age and symptom duration. RESULTS:In 60 patients, 252 radiographs were analysed. Baseline age and sym

SUBMITTER: Hissink Muller PCE 

PROVIDER: S-EPMC6727344 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature