Variation in the metabolites and α-glucosidase inhibitory activity of Cosmos caudatus at different growth stages.

ABSTRACT:

Background

Cosmos caudatus is an annual plant known for its medicinal value in treating several health conditions, such as high blood pressure, arthritis, and diabetes mellitus. The α-glucosidase inhibitory activity and total phenolic content of the leaf aqueous ethanolic extracts of the plant at different growth stages (6, 8. 10, 12 and 14 weeks) were determined in an effort to ascertain the best time to harvest the plant for maximum medicinal quality with respect to its glucose-lowering effects.

Methods

The aqueous ethanolic leaf extracts of C. caudatus were characterized by NMR and LC-MS/MS. The total phenolic content and α-glucosidase inhibitory activity were evaluated by the Folin-Ciocalteu method and α-glucosidase inhibitory assay, respectively. The statistical signifi

SUBMITTER: Wan-Nadilah WA 

PROVIDER: S-EPMC6727405 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature