Does the fortified milk with high iron dose improve the neurodevelopment of healthy infants? Randomized controlled trial.

ABSTRACT:

Background

Since iron plays an important role in several physiological processes, its deficiency but also overload may harm the development of children. The aim was to assess the effect of iron-fortified milk on the iron biochemical status and the neurodevelopment of children at 12 months of age.

Methods

Randomized controlled trial conducted in 133 Spanish children, allocated in two groups to receive formula milk fortified with 1.2 or 0.4 mg/100 mL of iron between 6 and 12 months of age. Psychomotor (PDI) and Mental (MDI) Development Index were assessed by the Bayley Scales before and after the intervention. Maternal obstetrical and psychosocial variables were recorded. The biochemical iron status of children was measured and data about breastfeeding, anthropometry and infec

SUBMITTER: Iglesias Vazquez L 

PROVIDER: S-EPMC6727503 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature