SamPler - a novel method for selecting parameters for gene functional annotation routines.

ABSTRACT:

Background

As genome sequencing projects grow rapidly, the diversity of organisms with recently assembled genome sequences peaks at an unprecedented scale, thereby highlighting the need to make gene functional annotations fast and efficient. However, the (high) quality of such annotations must be guaranteed, as this is the first indicator of the genomic potential of every organism. Automatic procedures help accelerating the annotation process, though decreasing the confidence and reliability of the outcomes. Manually curating a genome-wide annotation of genes, enzymes and transporter proteins function is a highly time-consuming, tedious and impractical task, even for the most proficient curator. Hence, a semi-automated procedure, which balances the two approaches, will increase the

SUBMITTER: Cruz F 

PROVIDER: S-EPMC6727554 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature