Positron emission tomography imaging of endogenous mu-opioid mechanisms during pain and migraine.

ABSTRACT: The enormous advancements in the medical imaging methods witnessed in the past decades have allowed clinical researchers to study the function of the human brain in vivo, both in health and disease. In addition, a better understanding of brain responses to different modalities of stimuli such as pain, reward, or the administration of active or placebo interventions has been achieved through neuroimaging methods. Although magnetic resonance imaging has provided important information regarding structural, hemodynamic, and metabolic changes in the central nervous system related to pain, magnetic resonance imaging does not address modulatory pain systems at the molecular level (eg, endogenous opioid). Such important information has been obtained through positron emission tomography, bringing i

SUBMITTER: DaSilva AF 

PROVIDER: S-EPMC6727995 | biostudies-literature | 2019 Jul-Aug

REPOSITORIES: biostudies-literature