Antidepressant continuation in pregnancy and risk of gestational diabetes.

ABSTRACT:

Purpose

Previous studies observed modestly higher risk of gestational diabetes (GDM) associated with antidepressant use in pregnancy, potentially due to confounding by indication. We assessed the association of antidepressant continuation in pregnancy with GDM, as well as blood glucose levels, after accounting for confounding.

Methods

We conducted a retrospective cohort study of singleton live births from 2001 to 2014 to women enrolled in Kaiser Permanente Washington, an integrated health care delivery system, utilizing electronic health data and linked Washington State birth records. We required that women have ≥1 antidepressant prescription fills ≤6 months before pregnancy. Women with an antidepressant fill during pregnancy were categorized as "continuers" (n = 1634); thos

SUBMITTER: Wartko PD 

PROVIDER: S-EPMC6728166 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature