Iron homeostasis during risperidone treatment in children and adolescents.

ABSTRACT:

Objective

Previous cross-sectional evidence has linked antipsychotic-related weight gain to reduced body iron concentration. Using longitudinal data, we examined the association between changes in weight following risperidone initiation or discontinuation and ferritin concentration.

Method

Study 1: Between April 2004 and September 2007, participants were enrolled from outpatient settings in a prospective randomized clinical trial comparing the efficacy of risperidone monotherapy to the combination of risperidone and behavior therapy in targeting disruptive behavior in 4- to 13-year-old children with DSM-IV-TR-based autism spectrum disorder. Study 2: Medically healthy 7- to 17-year-old participants in long-term open-label risperidone treatment at study entry returned for foll

SUBMITTER: Calarge CA 

PROVIDER: S-EPMC6728911 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature