Epidemiological distribution of genotypes of Giardia duodenalis in humans in Spain.

ABSTRACT:

Background

Although the distribution of Giardia duodenalis genotypes in humans has been increasingly reported in recent years, data on possible differences in pathogen transmission between age groups and virulence between genotypes are scarce. The purpose of this study is to investigate the genetic diversity of G. duodenalis in humans in Spain and compare the distribution of G. duodenalis assemblages A and B between children and adults and clinical presentations between the two genotypes.

Methods

In the present study, 125 microscopy-positive fecal samples were collected from humans in Spain over a 7-year period. PCR and sequence analyses of the triosephosphate isomerase, β-giardin and glutamate dehydrogenase genes were used to identify the multilocus genotypes of G. duodenal

SUBMITTER: Wang Y 

PROVIDER: S-EPMC6728964 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature