Risk of ischemic placental disease is increased following in vitro fertilization with oocyte donation: a retrospective cohort study.

ABSTRACT:

Purpose

Assess the risk of ischemic placental disease (IPD) among in vitro fertilization (IVF; donor and autologous) pregnancies compared with non-IVF pregnancies.

Methods

This was a retrospective cohort study of deliveries from 2000 to 2015 at a tertiary hospital. The exposures, donor, and autologous IVF, were compared with non-IVF pregnancies and donor IVF pregnancies were also compared with autologous IVF pregnancies. The outcome was IPD (preeclampsia, placental abruption, small for gestational age (SGA), or intrauterine fetal demise due to placental insufficiency). We defined SGA as birthweight < 10th percentiles for gestational age and sex. A secondary analysis restricted SGA to < 3rd percentile.

Results

Of 69,084 deliveries in this cohort, 262 resulted from dono

SUBMITTER: Modest AM 

PROVIDER: S-EPMC6730979 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature