Ontology highlight
ABSTRACT:
SUBMITTER: Zhu J
PROVIDER: S-EPMC6731061 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Zhu Jinsheng J Lau Kelvin K Puschmann Robert R Harmel Robert K RK Zhang Youjun Y Pries Verena V Gaugler Philipp P Broger Larissa L Dutta Amit K AK Jessen Henning J HJ Schaaf Gabriel G Fernie Alisdair R AR Hothorn Ludwig A LA Fiedler Dorothea D Hothorn Michael M
eLife 20190822
Many eukaryotic proteins regulating phosphate (Pi) homeostasis contain SPX domains that are receptors for inositol pyrophosphates (PP-InsP), suggesting that PP-InsPs may regulate Pi homeostasis. Here we report that deletion of two diphosphoinositol pentakisphosphate kinases VIH1/2 impairs plant growth and leads to constitutive Pi starvation responses. Deletion of phosphate starvation response transcription factors partially rescues vih1 vih2 mutant phenotypes, placing diphosphoinositol pentakisp ...[more]