Relationships of maternal body mass index and plasma biomarkers with childhood body mass index and adiposity at 6 years: The Children of SCOPE study.

ABSTRACT:

Background

Maternal obesity has been implicated in the origins of childhood obesity through a suboptimal environment in-utero.

Objective

We examined relationships of maternal early pregnancy body mass index (BMI), overweight/obesity, and plasma biomarkers of obesity, inflammation, insulin resistance, and placental function with measures of childhood BMI and adiposity.

Methods

BMI z-score, sum of skinfold thicknesses (SST), body fat percentage (BFP, by bioelectrical impedance), and waist, arm, and hip circumferences were measured in 1173 6-year-old children of nulliparous pregnant women in the Screening for Pregnancy Endpoints (SCOPE) study, New Zealand. Relationships of maternal early pregnancy (15 weeks' gestation) BMI and biomarkers with these childhood anthropometr

SUBMITTER: Dalrymple KV 

PROVIDER: S-EPMC6731120 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature