Efficacy of a new local limb salvage treatment for limb-threatening diabetic foot wounds - a randomized controlled study.

ABSTRACT:

Background

Diabetic foot ulcer (DFU) is the main risk factor for nontraumatic lower-limb amputation. We hypothesized that by reversing the offending local tissue factors resulting from the low tissue supply of oxygen, inefficient fuel metabolism and acidosis, we can eradicate the infection and help to promote healing. This might be enhanced with the help of an innovated local preparation (PEDYPHAR^®) through its enriched alkaline ointment base and the regenerating growth factors of Royal Jelly (RJ) plus the antimicrobial, immune-modulatory nutritional and other biochemical properties of RJ and Panthenol. We conducted this study to test the safety and efficacy of PEDYPHAR ointment as an adjuvant in limb salvage management for patients with limb-threatening diabetic foot wo

SUBMITTER: Yakoot M 

PROVIDER: S-EPMC6731465 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature