Incorporating household structure and demography into models of endemic disease.

ABSTRACT: The spread of infectious diseases is intimately linked with the strength and type of contact between individuals. Multiple observational and modelling studies have highlighted the importance of two forms of social mixing: age structure, where the likelihood of interaction between two individuals is determined by their ages; and household structure, which recognizes the much stronger contacts and hence transmission potential within the family setting. Age structure has been ubiquitous in predictive models of both endemic and epidemic infections, in part due to the ease of assessing someone's age. By contrast, although household structure is potentially the dominant heterogeneity, it has received less attention, in part due to an absence of the necessary methodology. Here, we develop the mod

SUBMITTER: Hilton J 

PROVIDER: S-EPMC6731502 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature