Evaluation of antimicrobial activity of chondrillasterol isolated from Vernonia adoensis (Asteraceae).

ABSTRACT:

Background

Bacteria have developed resistance to most of the current antibiotics. There is evidence suggesting that plant-derived compounds have a potential for interacting with biological processes. One of the plants commonly used in African ethnomedicine is Vernonia adoensis from the Asteraceae family. The leaves of the plant have been reported to have antimicrobial activity. Hence, the aim of this study was to isolate the bioactive compounds from the leaf extract and evaluate their antibacterial activity on Staphylococcus aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa. In addition, the effect of the isolated compound on biofilms of P. aeruginosa was determined.

Methods

Isolation of phytochemicals from the leaves of V. adoensis was done using column chromatograph

SUBMITTER: Mozirandi W 

PROVIDER: S-EPMC6731578 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature