A longitudinal functional magnetic resonance imaging study of task control circuits and bulimic symptoms over adolescence.

ABSTRACT:

Background

Previous cross-sectional findings from adolescents and adults with Bulimia Nervosa (BN) suggest disturbances in fronto-striatal and cingulo-opercular task control circuits that support self-regulatory processes, including the resolution of cognitive conflict. Herein, we used longitudinal data to examine the developmental trajectories of such disturbances and how the functioning of these circuits relates to changes in BN symptoms over adolescence.

Methods

Thirty-two adolescent females with BN symptoms and 28 healthy control (HC) adolescents participated in the study. Functional magnetic resonance images (fMRI) during performance of a Simon task were acquired at three time points within 2-year intervals over adolescence. From the initial sample, 70% and 30% of the p

SUBMITTER: Cyr M 

PROVIDER: S-EPMC6731764 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature