Congenital anomalies and associated risk factors in a Saudi population: a cohort study from pregnancy to age 2 years.

ABSTRACT: OBJECTIVE:To assess the three key issues for congenital anomalies (CAs) prevention and care, namely, CA prevalence, risk factor prevalence and survival, in a longitudinal cohort in Riyadh, Saudi Arabia. SETTING:Tertiary care centre, Riyadh, Saudi Arabia. PARTICIPANTS:Saudi women enrolled during pregnancy over 3 years and their 28 646 eligible pregnancy outcomes (births, stillbirths and elective terminations of pregnancy for foetal anomalies). The nested case-control study evaluated the CA risk factor profile of the underlying cohort. All CA cases (1179) and unaffected controls (1262) were followed through age 2 years. Referred mothers because of foetal anomaly and mothers who delivered outside the study centre and their pregnancy outcome were excluded. PRIMARY OUTCOME MEASURES:Prevalence a

SUBMITTER: Kurdi AM 

PROVIDER: S-EPMC6731804 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature