Modelling the lifetime cost-effectiveness of catheter ablation for atrial fibrillation with heart failure.

ABSTRACT:

Objectives

Assessing the cost-effectiveness credentials of this intervention in patients with concomitant atrial fibrillation (AF) and heart failure (HF) compared with usual medical therapy.

Design

A Markov model comprising two health states (ie, alive or dead) was constructed. The transition probabilities were directly derived from published Kaplan-Meier curves of the pivotal randomised controlled trial and extrapolated over the cohort's lifetime using recommended methods. Costs of catheter ablation, outpatient consultations, hospitalisation, medications and examinations were included. Resource use and unit costs were sourced from government websites or published literature. A lifetime horizon and a healthcare system perspective were taken. All costs and benefits were disco

SUBMITTER: Gao L 

PROVIDER: S-EPMC6731807 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature