Fatty liver index as a predictor of increased risk of cardiometabolic disease: finding from the Kuopio Ischaemic Heart Disease Risk Factor Study Cohort.

ABSTRACT: OBJECTIVE:Fatty liver disease (FLD), a global epidemic, is also a predictor of cardiometabolic disease (CMD) (type 2 diabetes or cardiovascular disease). Our objective was to examine whether progressive FLD, as assessed by fatty liver index (FLI), predicts increasing future CMD risk compared with relatively stable FLD, among middle-aged men. DESIGN:Prospective epidemiological study. SETTING:University affiliated research centre in Kuopio, Eastern Finland. PARTICIPANTS:Our subjects were 501 men without CMD during the initial 4-year follow-up in the Kuopio Ischaemic Heart Disease Risk Factor Study cohort. OUTCOME MEASURE:Over the initial 4-year follow-up, 135 men (26.9%) had a significant (≥10) FLI increase. The association of 4-year FLI increase with incident CMD was analysed in multivariab

SUBMITTER: Olubamwo OO 

PROVIDER: S-EPMC6731849 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature