Childhood adversities and 5-HTTLPR polymorphism as risk factors of substance use disorders: retrospective case-control study in Murcia (Spain).

ABSTRACT:

Objective

To explore the separate and joint associations of childhood adversities and 5-HTTLPR polymorphism as risk factors for substance use disorders among adults. : Design : Retrospective case-control study.

Setting

Cases from the substance unit and controls from a representative sample of the adult general population in the metropolitan area of Murcia (Spain).

Participants

Cases were defined as outpatients 18 years old or older currently in the treatment for alcohol, opioids or cocaine use disorders in the clinical unit. Controls were randomly selected among individuals without substance use disorders who participated in the Psychiatric Enquiry to General Population in Southeast Spain-Murcia (PEGASUS-Murcia) project, a cross-sectional study of a representat

SUBMITTER: Navarro-Mateu F 

PROVIDER: S-EPMC6731914 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature