Out-of-sequence DTP and measles vaccinations and child mortality in Guinea-Bissau: a reanalysis.

ABSTRACT:

Objectives

To assess whether the sequence of diphtheria-tetanus-pertussis vaccine (DTP) and measles vaccine (MV) was associated with child survival in a dataset previously used to assess non-specific effects of vaccines with no consideration of vaccination sequence.

Design

Prospective cohort study analysed using the landmark approach.

Setting

Bandim Health Project's Health and Demographic Surveillance System covering 100 village clusters in rural Guinea-Bissau. The recommended vaccination schedule was BCG and oral polio vaccine (OPV) at birth, DTP and OPV at 6, 10 and 14 weeks, MV at 9 months and booster DTP and OPV at 18 months of age.

Participants

Children aged 9-17 months (main analysis) and 18-35 months (secondary analysis: age of booster DTP) with vaccinat

SUBMITTER: Thysen SM 

PROVIDER: S-EPMC6731924 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature