Hepatitis B virus infection among oncohematologic disease patients in Central Brazil: prevalence, risk factors and immunization.

ABSTRACT:

Introduction

Carriers of oncohematological diseases are at high risk for hepatitis B virus (HBV) infection.

Objective and method

To investigate the epidemiology of HBV infection in Goiânia, Central Brazil, 322 individuals with oncohematological diseases (leukemias, Hodgkin lymphoma and non-Hodgkin lymphoma) were interviewed and blood samples were collected for the detection of serological markers of HBV-DNA by polymerase chain reaction (PCR). Medical records of participants were also reviewed.

Results

Non-Hodgkin's lymphomas (n=99) and chronic myeloid leukemia (n=108) were the most frequent oncohematological diseases. The overall prevalence of HBV was 13.97% (45/322). Of the total participants, 8.69% (28/322) presented isolated positivity for anti-HBs, suggesting low

SUBMITTER: Pessoni GC 

PROVIDER: S-EPMC6732398 | biostudies-literature | 2019 Jul - Sep

REPOSITORIES: biostudies-literature