Inadequate oxygen delivery index dose is associated with cardiac arrest risk in neonates following cardiopulmonary bypass surgery.

ABSTRACT:

Aim

To evaluate the Inadequate oxygen delivery (IDO₂) index dose as a predictor of cardiac arrest (CA) in neonates following congenital heart surgery.

Methods

Retrospective cohort study in 3 US pediatric cardiac intensive units (1/2011- 8/2016). Calculated IDO₂ index values were blinded to bedside clinicians and generated from data collected up to 30 days postoperatively, or until death or ECMO initiation. Control event data was collected from patients who did not experience CA or require ECMO. IDO₂ dose was computed over a 120-min window up to 30 min prior to the CA and control events. A multivariate logistic regression prediction model including the IDO₂ dose and presence or absence of a single ventricle (SV) was used. Model perf

SUBMITTER: Futterman C 

PROVIDER: S-EPMC6733252 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature