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Large-scale parallelization of nanomechanical mass spectrometry with weakly-coupled resonators.


ABSTRACT: Nanomechanical mass spectrometry is a recent technological breakthrough that enables the real-time analysis of single molecules. In contraposition to its extreme mass sensitivity is a limited capture cross-section that can hinder measurements in a practical setting. Here we show that weak-coupling between devices in resonator arrays can be used in nanomechanical mass spectrometry to parallelize the measurement. This coupling gives rise to asymmetric amplitude peaks in the vibrational response of a single nanomechanical resonator of the array, which coincide with the natural frequencies of all other resonators in the same array. A rigorous theoretical model is derived that explains the physical mechanisms and describes the practical features of this parallelization. We demonstrate the signi

SUBMITTER: Stassi S 

PROVIDER: S-EPMC6733932 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature