Compton imaging with ^99mTc for human imaging.

ABSTRACT: We have been developing a medical imaging system using a Compton camera and demonstrated the imaging ability of Compton camera for ^99mTc-DMSA accumulated in rat kidneys. In this study, we performed imaging experiments using a human body phantom to confirm its applicability to human imaging. Preliminary simulations were conducted using a digital phantom with varying activity ratios between the kidney and body trunk regions. Gamma rays (141 keV) were generated and detected by a Compton camera based on a silicon and cadmium telluride (Si/CdTe) detector. Compton images were reconstructed with the list mode median root prior expectation maximization method. The appropriate number of iterations of the condition was confirmed through simulations. The reconstructed Compton images reveal

SUBMITTER: Sakai M 

PROVIDER: S-EPMC6733951 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature