Mri-based cancer lesion analysis with 3d printed patient specific prostate cutting guides.

ABSTRACT: Purpose: MRI methods have improved diagnosis and treatment planning for prostate cancer. However, validation and standardization is needed to encourage widespread adoption of these methods. The purpose of this study was to improve validation methods by creating a prostate cutting guide and to develop a method for 3D comparison between MRI data and post-prostatectomy histological tissue slices. Methods: Prostate Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET)/MRI was performed on 10 patients with prostate cancer before and after chemohormonal treatment. Post-treatment images were used to design patient-specific prostate cutting guides that were used to create uniform thickness sections of surgically removed prostates. The thickness of the prostate tissue sl

SUBMITTER: Rutkowski DR 

PROVIDER: S-EPMC6734042 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature