Glucosuria Predicts the Severity of Puumala Hantavirus Infection.

ABSTRACT:

Introduction

Puumala hantavirus (PUUV) causes a mild type of hemorrhagic fever with renal syndrome characterized by acute kidney injury (AKI), increased capillary leakage, and thrombocytopenia. Albuminuria and hematuria in dipstick urine test at hospital admission are known to predict the severity of upcoming AKI.

Methods

We analyzed dipstick urine glucose in 195 patients with acute PUUV infection at hospital admission, and divided them into 2 categories according to the presence or absence of glucose in the dipstick urine test. Determinants of disease severity were analyzed in glucosuric and nonglucosuric patients.

Results

Altogether, 24 of 195 patients (12%) had glucosuria. The patients with glucosuria had more severe AKI than patients without glucosuria (median max

SUBMITTER: Tietavainen J 

PROVIDER: S-EPMC6734096 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature