Advanced visual network and cerebellar hyperresponsiveness to trigeminal nociception in migraine with aura.

ABSTRACT:

Background

Despite the growing body of advanced studies investigating the neuronal correlates of pain processing in patients with migraine without aura (MwoA), only few similar studies have been conducted in patients with migraine with aura (MwA). Therefore, we aimed to explore the functional brain response to trigeminal noxious heat stimulation in patients with MwA.

Methods

Seventeen patients with MwA and 15 age- and sex-matched healthy controls (HC) underwent whole-brain blood oxygen level-dependent (BOLD) fMRI during trigeminal noxious heat stimulation. To examine the specificity of any observed differences between patients with MwA and HC, the functional response of neural pathways to trigeminal noxious heat stimulation in patients with MwA was compared with 18 patients

SUBMITTER: Russo A 

PROVIDER: S-EPMC6734311 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature