Development and Emergence of Individual Variability in the Functional Connectivity Architecture of the Preterm Human Brain.

ABSTRACT: Individual variability in human brain networks underlies individual differences in cognition and behaviors. However, researchers have not conclusively determined when individual variability patterns of the brain networks emerge and how they develop in the early phase. Here, we employed resting-state functional MRI data and whole-brain functional connectivity analyses in 40 neonates aged around 31-42 postmenstrual weeks to characterize the spatial distribution and development modes of individual variability in the functional network architecture. We observed lower individual variability in primary sensorimotor and visual areas and higher variability in association regions at the third trimester, and these patterns are generally similar to those of adult brains. Different functional systems

SUBMITTER: Xu Y 

PROVIDER: S-EPMC6735255 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature