Usefulness of C-Reactive Protein in Differentiating Acute Leptospirosis and Dengue Fever in French Guiana.

ABSTRACT:

Objective

Leptospirosis and dengue fever (DF) are hard-to-differentiate diseases in cocirculating areas, especially during DF epidemics. Misdiagnosis and ensuing lack of antibiotic therapy can be detrimental in leptospirosis. The objective of this study was to identify factors that help differentiate acute leptospirosis from dengue fever on admission.

Method

Patients with leptospirosis (positive serology or polymerase chain reaction) were compared with patients with DF (positive nonstructural 1 [NS1] antigen) in a case-control study with age matching. Data on admission were compared using bivariate analysis and multivariate analysis.

Results

Seventy-two patients with leptospirosis were compared to 216 patients with DF. In bivariate analysis, the factors associated wit

SUBMITTER: Le Turnier P 

PROVIDER: S-EPMC6735690 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature