Alterations of peritoneal transport characteristics in dialysis patients with ultrafiltration failure: tissue and capillary components.

ABSTRACT:

Background

Ultrafiltration failure (UFF) in peritoneal dialysis (PD) patients is due to altered peritoneal transport properties leading to reduced capacity to remove excess water. Here, with the aim to establish the role of local alterations of the two major transport barriers, peritoneal tissue and capillary wall, we investigate changes in overall peritoneal transport characteristics in UFF patients in relation to corresponding local alterations of peritoneal tissue and capillary wall transport properties.

Methods

Six-hour dwell studies using 3.86% glucose solutions and radioisotopically labelled serum albumin added to dialysate as a volume marker were analysed in 31 continuous ambulatory PD patients, 20 with normal ultrafiltration (NUF) and 11 with UFF. For each patient, t

SUBMITTER: Stachowska-Pietka J 

PROVIDER: S-EPMC6735729 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature