Ascend: R package for analysis of single-cell RNA-seq data.

ABSTRACT:

Background

Recent developments in single-cell RNA sequencing (scRNA-seq) platforms have vastly increased the number of cells typically assayed in an experiment. Analysis of scRNA-seq data is multidisciplinary in nature, requiring careful consideration of the application of statistical methods with respect to the underlying biology. Few analysis packages exist that are at once robust, are computationally fast, and allow flexible integration with other bioinformatics tools and methods.

Findings

ascend is an R package comprising tools designed to simplify and streamline the preliminary analysis of scRNA-seq data, while addressing the statistical challenges of scRNA-seq analysis and enabling flexible integration with genomics packages and native R functions, including fast paral

SUBMITTER: Senabouth A 

PROVIDER: S-EPMC6735844 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature