Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death.

ABSTRACT:

Background

Risk of encapsulating peritoneal sclerosis (EPS) is strongly associated with the duration of peritoneal dialysis (PD), such that patients who have been on PD for some time may consider elective transfer to haemodialysis to mitigate the risk of EPS. There is a need to determine this risk to better inform clinical decision making, but previous studies have not allowed for the competing risk of death.

Methods

This study included new adult PD patients in Australia and New Zealand (ANZ; 1990-2010) or Scotland (2000-08) followed until 2012. Age, time on PD, primary renal disease, gender, data set and diabetic status were evaluated as predictors at the start of PD, then at 3 and 5 years after starting PD using flexible parametric competing risks models.

Results

In

SUBMITTER: Lambie M 

PROVIDER: S-EPMC6735880 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature