Distinguishing mild cognitive impairment from healthy aging and Alzheimer's Disease: The contribution of the INECO Frontal Screening (IFS).

ABSTRACT: Executive functions are affected differently in healthy aging, Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), and evaluating them is important for differential diagnosis. The INECO Frontal Screening (IFS) is a brief neuropsychological screening tool, developed to assess executive dysfunction in neurodegenerative disorders.

Goals

We aimed to examine whether and how MCI patients can be differentiated from cognitively healthy controls (HC) and mild to moderate AD patients based on IFS performance. We also explored how IFS scores are associated with age, years of education, and depressive/anxious symptoms (as assessed by the Hospital Anxiety and Depression Scale).

Method

IFS total scores were compared between 26 HC, 32 MCI and 21 mild to moderate AD patients. The t

SUBMITTER: Moreira HS 

PROVIDER: S-EPMC6736301 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature