Ontology highlight
ABSTRACT:
SUBMITTER: Zucker MR
PROVIDER: S-EPMC6736450 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Zucker Mark R MR Abruzzo Lynne V LV Herling Carmen D CD Barron Lynn L LL Keating Michael J MJ Abrams Zachary B ZB Heerema Nyla N Coombes Kevin R KR
Bioinformatics (Oxford, England) 20190901 17
<h4>Motivation</h4>Clonal heterogeneity is common in many types of cancer, including chronic lymphocytic leukemia (CLL). Previous research suggests that the presence of multiple distinct cancer clones is associated with clinical outcome. Detection of clonal heterogeneity from high throughput data, such as sequencing or single nucleotide polymorphism (SNP) array data, is important for gaining a better understanding of cancer and may improve prediction of clinical outcome or response to treatment. ...[more]