Vitamin D concentration and risk of Alzheimer disease: A meta-analysis of prospective cohort studies.

ABSTRACT:

Background

Considerable controversy exists on the association between serum vitamin D concentrations and Alzheimer disease (AD) risk. This study aimed to synthesize the association of serum vitamin D concentrations with AD in adults.

Methods

PubMed, Embase, and Cochrane library databases were searched for prospective cohort studies with data on serum vitamin D concentrations and AD risk.

Result

The studies that reported the adjusted relative risks (RRs) with 95% confidence intervals (CIs) of AD associated with serum vitamin D concentrations were included and subjected to subgroup analyses. Six prospective cohort studies with 1607 AD cases and 21,692 individuals were included in the meta-analysis. In 4 cohort studies with information about serum vitamin D concentration

SUBMITTER: Yang K 

PROVIDER: S-EPMC6736453 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature