Randomized Controlled Study of an Absorbable Vena Cava Filter in a Porcine Model.

ABSTRACT:

Purpose

To compare the safety and efficacy of an absorbable inferior vena cava (IVC) filter and a benchmark IVC filter in a porcine model.

Materials and methods

A randomized controlled Good Laboratory Practice study was performed in Domestic Yorkshire cross swine. Sixteen swine were implanted with an absorbable IVC filter (test device; Adient Medical, Pearland, Texas); 8 were implanted with a benchmark metal IVC filter (control device; Cook Medical, Bloomington, Indiana). All animals underwent rotational digital subtraction pulmonary angiography and cavography (anteroposterior and lateral) before filter deployment and 5 and 32 weeks after deployment. Terminal procedures and necropsy were performed at 32 weeks. The IVC, heart, lungs, liver, and kidneys were harvested at necro

SUBMITTER: Eggers M 

PROVIDER: S-EPMC6736596 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature