The association between colorectal sessile serrated adenomas/polyps and subsequent advanced colorectal neoplasia.

ABSTRACT:

Purpose

Colorectal cancer (CRC) screening guidelines recommend increased surveillance of individuals with sessile serrated adenomas/polyps (SSA/Ps), but there is uncertainty about the risk associated with SSA/Ps. We aimed to determine the association between SSA/Ps and subsequent advanced colorectal neoplasia.

Methods

This case-control study included Kaiser Permanente Washington (KPWA) members who received an index colonoscopy between 1/1/1998 and 12/31/2007, and had hyperplastic polyps (HPs) or SSA/Ps but no conventional adenomas according to study pathologist histologic review. Subsequent pathology reports and biopsies through 1/1/2013 were reviewed for advanced colorectal neoplasia. We linked to the Seattle-Puget Sound Surveillance Epidemiology and End Results (SEER) regi

SUBMITTER: Burnett-Hartman AN 

PROVIDER: S-EPMC6736607 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature